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Issue 15, 2012
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Immobilization-free screening of aptamers assisted by graphene oxide

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Abstract

Graphene oxide (GO) has the ability to separate free short ssDNA in heterogeneous solution. This feature is applied as a label free platform for screening of aptamers that bind to their target with high affinity and specificity. Herein, we report an aptamer selection strategy for Nampt protein based on GO.

Graphical abstract: Immobilization-free screening of aptamers assisted by graphene oxide

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Publication details

The article was received on 18 Oct 2011, accepted on 23 Nov 2011 and first published on 24 Nov 2011


Article type: Communication
DOI: 10.1039/C2CC16473F
Citation: Chem. Commun., 2012,48, 2071-2073
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    Immobilization-free screening of aptamers assisted by graphene oxide

    J. Park, R. Tatavarty, D. W. Kim, H. Jung and M. B. Gu, Chem. Commun., 2012, 48, 2071
    DOI: 10.1039/C2CC16473F

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