Jump to main content
Jump to site search

Issue 6, 2012
Previous Article Next Article

In situ nanochemical imaging of label-free drugs: a case study of antimalarials in Plasmodium falciparum-infected erythrocytes

Author affiliations

Abstract

We report here for the first time the in vitrolocalization of unlabeled antimalarial drugs with high spatial resolution. This strategy further enhances our understanding of the action mechanisms of antimalarial drugs. Our approach may be applied to a wide range of domains where quantitative chemical imaging of drugs at the sub-cellular level appears critical.

Graphical abstract: In situ nanochemical imaging of label-free drugs: a case study of antimalarials in Plasmodium falciparum-infected erythrocytes

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Oct 2011, accepted on 18 Nov 2011 and first published on 21 Nov 2011


Article type: Communication
DOI: 10.1039/C1CC16211J
Citation: Chem. Commun., 2012,48, 910-912
  •   Request permissions

    In situ nanochemical imaging of label-free drugs: a case study of antimalarials in Plasmodium falciparum-infected erythrocytes

    F. Dubar, S. Bohic, C. Slomianny, J. Morin, P. Thomas, H. Kalamou, Y. Guérardel, P. Cloetens, J. Khalife and C. Biot, Chem. Commun., 2012, 48, 910
    DOI: 10.1039/C1CC16211J

Search articles by author

Spotlight

Advertisements