A novel exonuclease III aided amplification method for sensitive nucleic acid detection based on single walled carbon nanotube induced quenching

Hui Chen; Jiaqin Wang; Guohai Liang; Peng Zhang; Jilie Kong

doi:10.1039/C1CC16127J

A novel exonuclease III aided amplification method for sensitive nucleic acid detection based on single walled carbon nanotube induced quenching

Hui Chen,^a Jiaqin Wang,^a Guohai Liang,^a Peng Zhang^a and Jilie Kong*^a

* Corresponding authors

^a Department of Chemistry, CAM & IBS, Fudan University, Shanghai, P.R. China
E-mail: jlkong@fudan.edu.cn
Fax: +86 21 65641740
Tel: +86 21 65642405

Abstract

We describe herein a novel exonuclease III aided amplification method based on single walled carbon nanotube quenching (EASQ) for sensitive and convenient nucleic acid detection, which enabled 80-fold decrease of detection limit for HIV1 DNA assay compared with no target recycling.

Supplementary files

Publication details

The article was received on 01 Oct 2011, accepted on 09 Nov 2011 and first published on 22 Nov 2011

Article type: Communication

DOI: 10.1039/C1CC16127J

Citation: Chem. Commun., 2012,48, 269-271

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A novel exonuclease III aided amplification method for sensitive nucleic acid detection based on single walled carbon nanotube induced quenching

H. Chen, J. Wang, G. Liang, P. Zhang and J. Kong, Chem. Commun., 2012, 48, 269
DOI: 10.1039/C1CC16127J
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Chemical Communications

A novel exonuclease III aided amplification method for sensitive nucleic acid detection based on single walled carbon nanotube induced quenching

Abstract

Supplementary files

Publication details

A novel exonuclease III aided amplification method for sensitive nucleic acid detection based on single walled carbon nanotube induced quenching

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