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Issue 2, 2012
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Graphene oxide-protected DNA probes for multiplex microRNA analysis in complex biological samples based on a cyclic enzymatic amplification method

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Abstract

Based on graphene oxide-protected DNA probes, we have developed a cyclic enzymatic amplification method for sensitive miRNA detection in complex biological samples. By using the quenching nature of graphene oxide for multiple fluorophores, this method can distinguish highly similar miRNA sequences and detect them simultaneously.

Graphical abstract: Graphene oxide-protected DNA probes for multiplex microRNA analysis in complex biological samples based on a cyclic enzymatic amplification method

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Publication details

The article was received on 31 Aug 2011, accepted on 22 Sep 2011 and first published on 05 Oct 2011


Article type: Communication
DOI: 10.1039/C1CC15412E
Citation: Chem. Commun., 2012,48, 194-196
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    Graphene oxide-protected DNA probes for multiplex microRNA analysis in complex biological samples based on a cyclic enzymatic amplification method

    L. Cui, X. Lin, N. Lin, Y. Song, Z. Zhu, X. Chen and C. J. Yang, Chem. Commun., 2012, 48, 194
    DOI: 10.1039/C1CC15412E

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