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Issue 10, 2012
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A modular system for regeneration of NAD cofactors using graphite particles modified with hydrogenase and diaphorase moieties

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Abstract

Pyrolytic graphite particles modified with hydrogenase and an NAD+/NADH cycling enzyme provide a modular heterogeneous catalyst system for regeneration of oxidised or reduced nicotinamide cofactors using H2 and H+ as electron source or sink. Particles can be tuned for cofactor supply under different conditions by appropriate choice of hydrogenase.

Graphical abstract: A modular system for regeneration of NAD cofactors using graphite particles modified with hydrogenase and diaphorase moieties

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Publication details

The article was received on 04 Aug 2011, accepted on 21 Sep 2011 and first published on 10 Oct 2011


Article type: Communication
DOI: 10.1039/C1CC14826E
Citation: Chem. Commun., 2012,48, 1589-1591
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    A modular system for regeneration of NAD cofactors using graphite particles modified with hydrogenase and diaphorase moieties

    H. A. Reeve, L. Lauterbach, P. A. Ash, O. Lenz and K. A. Vincent, Chem. Commun., 2012, 48, 1589
    DOI: 10.1039/C1CC14826E

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