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Issue 10, 2012
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Modular synthesis of supramolecular ureidopyrimidinonepeptide conjugates using an oxime ligation strategy

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Abstract

A convenient method to prepare supramolecular bioconjugates in a facile and scalable manner is by a modular approach, whereby self-assembling units and peptides are coupled using oxime chemistry. We here report syntheses of bioactive ureidopyrimidinone-based peptide conjugates, and their resultant self-assembly into fibrous structures.

Graphical abstract: Modular synthesis of supramolecular ureidopyrimidinone–peptide conjugates using an oxime ligation strategy

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Publication details

The article was received on 31 Jul 2011, accepted on 07 Oct 2011 and first published on 18 Oct 2011


Article type: Communication
DOI: 10.1039/C1CC14728E
Citation: Chem. Commun., 2012,48, 1452-1454
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    Modular synthesis of supramolecular ureidopyrimidinonepeptide conjugates using an oxime ligation strategy

    R. E. Kieltyka, M. M. C. Bastings, G. C. van Almen, P. Besenius, E. W. L. Kemps and P. Y. W. Dankers, Chem. Commun., 2012, 48, 1452
    DOI: 10.1039/C1CC14728E

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