Jump to main content
Jump to site search

Issue 10, 2012
Previous Article Next Article

Facile synthesis and altered ionization efficiency of diverse Nε-alkyllysine-containing peptides

Author affiliations

Abstract

Protein lysine methylation is a biologically-important posttranslational modification. Given the increased use of alkyllysine-containing peptides to study protein methylation, we describe an efficient solid-phase synthesis to access various alkyllysine-containing peptides. As an exemplary application, we evaluated how ionization efficiency of the alkyllysine peptides affects mass spectrometric analysis.

Graphical abstract: Facile synthesis and altered ionization efficiency of diverse Nε-alkyllysine-containing peptides

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 31 Jul 2011, accepted on 19 Sep 2011 and first published on 30 Sep 2011


Article type: Communication
DOI: 10.1039/C1CC14711K
Citation: Chem. Commun., 2012,48, 1514-1516
  •   Request permissions

    Facile synthesis and altered ionization efficiency of diverse Nε-alkyllysine-containing peptides

    D. Chakraborty, K. Islam and M. Luo, Chem. Commun., 2012, 48, 1514
    DOI: 10.1039/C1CC14711K

Search articles by author