Issue 9, 2012
From the journal:

Analyst

A simple fluorometric assay for DNA exonuclease activity based on graphene oxide†

Jieon Leea  and  Dal-Hee Min*a  

* Corresponding authors

a Department of Chemistry, Seoul National University, Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea
E-mail: dalheemin@snu.ac.kr
Web: http://sites.google.com/site/dalheemin/
Fax: +82-2-875-6636
Tel: +82-2-880-4338

Abstract

A new assay platform for DNA exonuclease activity is developed based on the preferential binding of single-stranded DNA (ssDNA) over double-stranded DNA (dsDNA) to graphene oxide. This approach allows a simple and quantitative activity measurement in a short time at low cost.

Graphical abstract: A simple fluorometric assay for DNA exonuclease activity based on graphene oxide

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Article information

DOI
https://doi.org/10.1039/C2AN16214H
Article type
Communication
Submitted
06 Dec 2011
Accepted
27 Feb 2012
First published
13 Mar 2012

Analyst, 2012,137, 2024-2026

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A simple fluorometric assay for DNA exonuclease activity based on graphene oxide

J. Lee and D. Min, Analyst, 2012, 137, 2024 DOI: 10.1039/C2AN16214H

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