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Issue 4, 2012
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Spectrophotometric detection of tyrosinase activity based on boronic acid-functionalized gold nanoparticles

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Abstract

A spectrophotometric method for the detection of tyrosinase activity is developed by utilizing the product-triggered aggregation of boronic acid-functionalized gold nanoparticles. Based on the changes of absorbance in UV-visible spectra, the assay shows extremely high sensitivity and lowered limit of detection of 1 × 10−10 u mL−1.

Graphical abstract: Spectrophotometric detection of tyrosinase activity based on boronic acid-functionalized gold nanoparticles

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Publication details

The article was received on 09 Nov 2011, accepted on 15 Dec 2011 and first published on 03 Jan 2012


Article type: Communication
DOI: 10.1039/C2AN16085D
Citation: Analyst, 2012,137, 823-825
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    Spectrophotometric detection of tyrosinase activity based on boronic acid-functionalized gold nanoparticles

    S. Li, L. Mao, Y. Tian, J. Wang and N. Zhou, Analyst, 2012, 137, 823
    DOI: 10.1039/C2AN16085D

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