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Issue 3, 2012
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Surface enhanced Raman scattering for multiplexed detection

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Abstract

The multiplexed detection of biological analytes from complex mixtures is of crucial importance for the future of intelligent management and detection of disease. This review focuses on recent advances in the use of surface enhanced Raman scattering (SERS) spectroscopy as an analytical technique that can deliver multiplexed detection for a variety of biological target in increasingly complex media. The use of SERS has developed from the multipelxed detection of custom dye molecules to biomolecules such as DNA and proteins. Recent work has also shown the capability of SERS multiplexing for in vivo as well as in vitro applications.

Graphical abstract: Surface enhanced Raman scattering for multiplexed detection

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Publication details

The article was received on 19 Oct 2011, accepted on 25 Nov 2011 and first published on 20 Dec 2011


Article type: Minireview
DOI: 10.1039/C2AN15979A
Citation: Analyst, 2012,137, 545-554
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    Surface enhanced Raman scattering for multiplexed detection

    J. A. Dougan and K. Faulds, Analyst, 2012, 137, 545
    DOI: 10.1039/C2AN15979A

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