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Issue 5, 2012
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Novel nanobiotechnological concepts in electrochemical biosensors for the analysis of toxins

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Abstract

This article gives an overview of the biosensors for the analysis of mycotoxins, marine toxins and cyanobacterial toxins, describing in depth the electrochemical biosensors that incorporate nanobiotechnological concepts. Firstly, it presents tailor-designed biomolecules, such as recombinant enzymes, recombinant antibody fragments and aptamers as novel biorecognition elements in biosensors. It also reviews the use of metallic nanoparticles (NPs) and carbon nanotubes (CNTs) aiming at improving the electrochemical transduction strategies. Finally, the exploitation of magnetic particles (MPs) as immobilisation carriers in flow-systems and the development of arrays are also described. The incorporation of these nanobiotechnological concepts provides with electrochemical biosensors with superior analytical performance in terms of specificity, sensitivity, stability and analysis time.

Graphical abstract: Novel nanobiotechnological concepts in electrochemical biosensors for the analysis of toxins

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Publication details

The article was received on 11 Aug 2011, accepted on 06 Dec 2011 and first published on 11 Jan 2012


Article type: Critical Review
DOI: 10.1039/C2AN15736E
Citation: Analyst, 2012,137, 1055-1067
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    Novel nanobiotechnological concepts in electrochemical biosensors for the analysis of toxins

    M. Campàs, D. Garibo and B. Prieto-Simón, Analyst, 2012, 137, 1055
    DOI: 10.1039/C2AN15736E

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