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Issue 22, 2011
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Cubosomes for ruthenium complex delivery: formulation and characterization

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Abstract

An amphiphilic ruthenium-based molecule (DOPURu) with potential antineoplastic activity has been synthesized, and its aggregation behavior in the presence of phospholipids has been investigated. A very rich variety of aggregates has been found, spanning from vesicles to cubic bicontinuous phases. Cubosomes here presented represent one of the first systems with potential use for medical therapy.

Graphical abstract: Cubosomes for ruthenium complex delivery: formulation and characterization

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Publication details

The article was received on 13 Jul 2011, accepted on 12 Sep 2011 and first published on 03 Oct 2011


Article type: Communication
DOI: 10.1039/C1SM06323E
Citation: Soft Matter, 2011,7, 10577-10580
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    Cubosomes for ruthenium complex delivery: formulation and characterization

    G. Mangiapia, M. Vaccaro, G. D'Errico, H. Frielinghaus, A. Radulescu, V. Pipich, A. M. Carnerup and L. Paduano, Soft Matter, 2011, 7, 10577
    DOI: 10.1039/C1SM06323E

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