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Issue 13, 2011
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Synthesis of composite microgel capsules by ultrasonic spray combined with in situ crosslinking

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Abstract

Composite microgel capsules were fabricated through an ultrasonic spray accompanied by in situ surface crosslinking between glycol chitosan (GC) and benzaldehyde capped poly(ethylene glycol) (OHC–PEG–CHO) in the nebulized droplets. The methodology enables a selective one-pot encapsulation for different functional species inside the interior cavity or within the shell. Herein lithium phthalocyanine (LiPc) microcrystals and citrate stabilized iron oxide (Fe3O4) nanoparticles were selected as model materials for the functionalization, which led to the electron paramagnetic resonance (EPR) and superparamagnetic dual performance of the composite microgel capsules. This shows the potential of the microgel capsules in diagnosis and targeting delivery applications.

Graphical abstract: Synthesis of composite microgel capsules by ultrasonic spray combined with in situ crosslinking

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Publication details

The article was received on 21 Feb 2011, accepted on 04 May 2011 and first published on 27 May 2011


Article type: Paper
DOI: 10.1039/C1SM05305A
Citation: Soft Matter, 2011,7, 6144-6150
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    Synthesis of composite microgel capsules by ultrasonic spray combined with in situ crosslinking

    L. Zhao, L. Zhu, Q. Wang, J. Li, C. Zhang, J. Liu, X. Qu, G. He, Y. Lu and Z. Yang, Soft Matter, 2011, 7, 6144
    DOI: 10.1039/C1SM05305A

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