Structurally simple lipid bilayer transport agents for chloride and bicarbonate

Natalie J. Andrews; Cally J. E. Haynes; Mark E. Light; Stephen J. Moore; Christine C. Tong; Jeffery T. Davis; William A. Harrell Jr.; Philip A. Gale

doi:10.1039/C0SC00503G

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Chemical Science

Issue 2, 2011

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Structurally simple lipid bilayer transport agents for chloride and bicarbonate

Natalie J. Andrews , Cally J. E. Haynes , Mark E. Light , Stephen J. Moore , Christine C. Tong , Jeffery T. Davis , William A. Harrell Jr. and Philip A. Gale

Chem. Sci., 2011, 2, 256-260

DOI: 10.1039/C0SC00503G
Received 26 Sep 2010, Accepted 21 Oct 2010
First published on the web 23 Nov 2010

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Abstract
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A new series of structurally simple compounds containing thiourea groups have been shown by a combination of ion-selective electrode and ¹³C NMR techniques to be potent chloride-bicarbonate exchange agents that function at low concentration in POPC and POPC/cholesterol membranes.

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Synthetic procedures, NMR spectra, anion transport studies, crystal structures of compounds 5 and 8.
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Articles By

Natalie J. Andrews
Cally J. E. Haynes
Mark E. Light
Stephen J. Moore
Christine C. Tong
Jeffery T. Davis
William A. Harrell Jr.
Philip A. Gale

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Chemical Science

Structurally simple lipid bilayer transport agents for chloride and bicarbonate

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