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Issue 2, 2011
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Azomethine ylide annulations: facile access to polycyclic ring systems

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Abstract

New annulation reactions of azomethine ylides are reported. Amino acids react with aldehydes that are linked to a pronucleophile (e.g. an indole subunit) to provide rapid access to polycyclic ring systems. Simple amines can also be used in place of amino acids.

Graphical abstract: Azomethine ylide annulations: facile access to polycyclic ring systems

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Publication details

The article was received on 12 Aug 2010, accepted on 05 Oct 2010 and first published on 27 Oct 2010


Article type: Edge Article
DOI: 10.1039/C0SC00432D
Citation: Chem. Sci., 2011,2, 233-236
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    Azomethine ylide annulations: facile access to polycyclic ring systems

    C. Zhang, D. Das and D. Seidel, Chem. Sci., 2011, 2, 233
    DOI: 10.1039/C0SC00432D

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