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A novel strategy of chemical modification for rate enhancement of 10–23 DNAzyme: a combination of A9 position and 8-aza-7-deaza-2′-deoxyadenosine analogs

Junlin He,a   Di Zhang,b   Qi Wang,a   Xia Wei,a   Maosheng Cheng*b and   Keliang Liu*a  
Corresponding authors
Beijing Institute of Pharmacology and Toxicology, 27 Taiping Road, Beijing, China
E-mail: keliangliu55@126.com
Fax: +86-10-68211656
Tel: +86-10-68169363
School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, China
Org. Biomol. Chem., 2011,9, 5728-5736

DOI: 10.1039/C1OB05065F
Received 12 Jan 2011, Accepted 16 May 2011
First published online 16 May 2011
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