Jump to main content
Jump to site search

Issue 15, 2011
Previous Article Next Article

N-Fmoc-α-sulfo-β-alanine: a versatile building block for the water solubilisation of chromophores and fluorophores by solid-phase strategy

Author affiliations

Abstract

An easy and efficient solid-phase synthesis strategy to obtain rapidly water-soluble chromophores/fluorophores in highly pure form has been developed. This first successful use of N-Fmoc-α-sulfo-β-alanine as a SPPS building block opens the way to the future development of promising direct “on-resin” peptide labelling and water-solubilising methods.

Graphical abstract: N-Fmoc-α-sulfo-β-alanine: a versatile building block for the water solubilisation of chromophores and fluorophores by solid-phase strategy

Back to tab navigation

Supplementary files

Publication details

The article was received on 09 May 2011, accepted on 27 May 2011 and first published on 27 May 2011


Article type: Communication
DOI: 10.1039/C1OB05730H
Citation: Org. Biomol. Chem., 2011,9, 5337-5342
  •   Request permissions

    N-Fmoc-α-sulfo-β-alanine: a versatile building block for the water solubilisation of chromophores and fluorophores by solid-phase strategy

    A. Romieu, T. Bruckdorfer, G. Clavé, V. Grandclaude, C. Massif and P. Renard, Org. Biomol. Chem., 2011, 9, 5337
    DOI: 10.1039/C1OB05730H

Search articles by author

Spotlight

Advertisements