Issue 5, 2011
From the journal:

Organic & Biomolecular Chemistry

Pd/Cu-catalyzed cascade Sonogashira coupling/cyclization reactions to highly substituted 3-formyl furans†

Jingyu Yang,a   Chengyu Wang,a   Xin Xie,a   Hongfeng Li,a   Ende Lia  and  Yanzhong Li*a  

* Corresponding authors

a Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Institute of Medicinal Chemistry, Department of Chemistry, East China Normal University, 3663 North Zhongshan Road, Shanghai, People's Republic of China
E-mail: yzli@chem.ecnu.edu.cn
Fax: (+86) 021-62233969

Abstract

An efficient palladium/copper-catalyzed approach to the synthesis of highly substituted 3-formyl furans from the reactions of readily available α-bromoenaminones with terminal alkynes has been developed. This methodology was realized by the cascade reactions of Sonogashira coupling and the subsequent intramolecular cyclization.

Graphical abstract: Pd/Cu-catalyzed cascade Sonogashira coupling/cyclization reactions to highly substituted 3-formyl furans

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C0OB00985G
Article type
Communication
Submitted
05 Nov 2010
Accepted
17 Dec 2010
First published
20 Dec 2010

Org. Biomol. Chem., 2011,9, 1342-1346

Permissions

Request permissions

Pd/Cu-catalyzed cascade Sonogashira coupling/cyclization reactions to highly substituted 3-formyl furans

J. Yang, C. Wang, X. Xie, H. Li, E. Li and Y. Li, Org. Biomol. Chem., 2011, 9, 1342 DOI: 10.1039/C0OB00985G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements