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Issue 6, 2011
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Quantum dot–aptamer nanoprobes for recognizing and labeling influenza A virus particles

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Abstract

The fluorescence labeling of viruses is a useful technology for virus detection and imaging. By combining the excellent fluorescence properties of quantum dots (QDs) with the high affinity and specificity of aptamers, we constructed a QD–aptamer probe. The aptamer A22, against the hemagglutinin of influenza A virus, was linked to QDs, producing the QD–A22 probe. Fluorescence imaging and transmission electron microscopy showed that the QD–A22 probe could specifically recognize and label influenza A virus particles. This QD labeling technique provides a new strategy for labeling virus particles for virus detection and imaging.

Graphical abstract: Quantum dot–aptamer nanoprobes for recognizing and labeling influenza A virus particles

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Publication details

The article was received on 28 Feb 2011, accepted on 25 Mar 2011 and first published on 21 Apr 2011


Article type: Communication
DOI: 10.1039/C1NR10218D
Citation: Nanoscale, 2011,3, 2454-2457
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    Quantum dot–aptamer nanoprobes for recognizing and labeling influenza A virus particles

    Z. Cui, Q. Ren, H. Wei, Z. Chen, J. Deng, Z. Zhang and X. Zhang, Nanoscale, 2011, 3, 2454
    DOI: 10.1039/C1NR10218D

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