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Issue 6, 2011
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Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

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Abstract

We report the effect of carboxyl functionalization of graphene in pacifying its strong hydrophobic interaction with cells and associated toxic effects. Pristine graphene was found to accumulate on the cell membrane causing high oxidative stress leading to apoptosis, whereas carboxyl functionalized hydrophilic graphene was internalized by the cells without causing any toxicity.

Graphical abstract: Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

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Publication details

The article was received on 14 Feb 2011, accepted on 15 Apr 2011 and first published on 12 May 2011


Article type: Communication
DOI: 10.1039/C1NR10172B
Citation: Nanoscale, 2011,3, 2461-2464
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    Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

    A. Sasidharan, L. S. Panchakarla, P. Chandran, D. Menon, S. Nair, C. N. R. Rao and M. Koyakutty, Nanoscale, 2011, 3, 2461
    DOI: 10.1039/C1NR10172B

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