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Issue 4, 2011
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Polyethylenimine–carbon nanotube nanohybrids for siRNA-mediated gene silencing at cellular level

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Abstract

Carbon nanotubes (CNTs) covalently modified with low molecular weight polyethylenimine (PEI) are able to bind and deliver siRNA to cells with higher efficacy than a reference lipidic carrier. The performances of the nanohybrid are rationalized by the combination of the cell penetration and endosomal escape properties of CNTs and PEI, respectively.

Graphical abstract: Polyethylenimine–carbon nanotube nanohybrids for siRNA-mediated gene silencing at cellular level

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Publication details

The article was received on 19 Dec 2010, accepted on 15 Jan 2011 and first published on 07 Feb 2011


Article type: Communication
DOI: 10.1039/C0NR01005G
Citation: Nanoscale, 2011,3, 1461-1464
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    Polyethylenimine–carbon nanotube nanohybrids for siRNA-mediated gene silencing at cellular level

    S. Foillard, G. Zuber and E. Doris, Nanoscale, 2011, 3, 1461
    DOI: 10.1039/C0NR01005G

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