Nanoporous alumina-based interferometric transducers ennobled

Roman Dronov; Andrew Jane; Joseph G. Shapter; Alastair Hodges; Nicolas H. Voelcker

doi:10.1039/C0NR00897D

Nanoporous alumina-based interferometric transducers ennobled

Roman Dronov,^a Andrew Jane,^a Joseph G. Shapter,^a Alastair Hodges^b and Nicolas H. Voelcker*^a

* Corresponding authors

^a School of Chemical and Physical Sciences, Flinders University, Australia
E-mail: nico.voelcker@flinders.edu.au
Fax: +61 88201 2905
Tel: +61 882015338

^b Universal Biosensors, Rowville, Australia

Abstract

A high fidelity interferometric transducer is designed based on platinum-coated nanoporous alumina films. The ultrathin metal coating significantly improves fidelity of the interferometric fringe patterns in aqueous solution and increases the signal-to-noise ratio. The performance of this transducer is tested with respect to refractive index unit (RIU) sensitivity measured as a change in effective optical thickness (EOT) in response to a solvent change and compared to porous silicon based transducers. RIU sensitivity in the order of 55% is attainable for porous alumina providing excellent signal-to-noise ratio, which exceeds the sensitivity of current interferometric transducers. Finally, as a proof-of-principle, we demonstrate biosensing with two distinct immunoglobulin antibodies.

Supplementary files

Publication details

The article was received on 24 Nov 2010, accepted on 15 Jan 2011 and first published on 24 Feb 2011

Article type: Paper

DOI: 10.1039/C0NR00897D

Citation: Nanoscale, 2011,3, 3109-3114

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Nanoporous alumina-based interferometric transducers ennobled

R. Dronov, A. Jane, J. G. Shapter, A. Hodges and N. H. Voelcker, Nanoscale, 2011, 3, 3109
DOI: 10.1039/C0NR00897D
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Nanoscale

Nanoporous alumina-based interferometric transducers ennobled

Abstract

Supplementary files

Publication details

Nanoporous alumina-based interferometric transducers ennobled

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