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Issue 3, 2011
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An enzyme-sensitive probe for photoacoustic imaging and fluorescence detection of protease activity

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Abstract

A gold nanocage and dye conjugate has been demonstrated for use with photoacoustic imaging and fluorescence detection of protease activity. The detection sensitivity could be maximized by using gold nanocages with a localized surface plasmon resonance peak away from the emission peak of the dye. These hybrids can be potentially used as multimodal contrast agents for molecular imaging.

Graphical abstract: An enzyme-sensitive probe for photoacoustic imaging and fluorescence detection of protease activity

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Publication details

The article was received on 16 Nov 2010, accepted on 07 Dec 2010 and first published on 11 Jan 2011


Article type: Communication
DOI: 10.1039/C0NR00874E
Citation: Nanoscale, 2011,3, 950-953
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    An enzyme-sensitive probe for photoacoustic imaging and fluorescence detection of protease activity

    X. Xia, M. Yang, L. K. Oetjen, Y. Zhang, Q. Li, J. Chen and Y. Xia, Nanoscale, 2011, 3, 950
    DOI: 10.1039/C0NR00874E

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