Piperazic acid-containing natural products: Isolation, biological relevance and total synthesis

Alexander J. Oelke; David J. France; Tatjana Hofmann; Georg Wuitschik; Steven V. Ley

doi:10.1039/C1NP00041A

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Natural Product Reports

Issue 8, 2011

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Piperazic acid-containing natural products: Isolation, biological relevance and total synthesis

Alexander J. Oelke , David J. France , Tatjana Hofmann , Georg Wuitschik and Steven V. Ley

Nat. Prod. Rep., 2011, 28, 1445-1471

DOI: 10.1039/C1NP00041A
Received 04 May 2011, First published on the web 05 Jul 2011

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Abstract
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Covering: up to 2010

Since their first discovery in 1959, natural products containing the piperazic acid motif have been isolated from a variety of sources and exhibit diverse biological activity profiles. This review provides information about their isolation and biological activities, and presents an overview of recent total syntheses of these molecules.

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Alexander J. Oelke
David J. France
Tatjana Hofmann
Georg Wuitschik
Steven V. Ley

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Piperazic acid-containing natural products: Isolation, biological relevance and total synthesis

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