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Issue 1, 2011
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Chlorosulfolipids: Structure, synthesis, and biological relevance

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Abstract

Chlorosulfolipids have been isolated from freshwater algae and from toxic mussels. They appear to have a structural role in algal membranes and have been implicated in Diarrhetic Shellfish Poisoning. Further fascinating aspects of these compounds include their stereochemically complex polychlorinated structures and the resulting strong conformational biases, and their poorly understood (yet surely compelling) biosynthesis. Discussions of each of these topics and of efforts in structural and stereochemical elucidation and synthesis are the subject of this Highlight.

Graphical abstract: Chlorosulfolipids: Structure, synthesis, and biological relevance

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Publication details

The article was received on 16 Sep 2010 and first published on 02 Dec 2010


Article type: Highlight
DOI: 10.1039/C0NP00044B
Citation: Nat. Prod. Rep., 2011,28, 15-25
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    Chlorosulfolipids: Structure, synthesis, and biological relevance

    D. K. Bedke and C. D. Vanderwal, Nat. Prod. Rep., 2011, 28, 15
    DOI: 10.1039/C0NP00044B

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