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Renovis, Inc. (a wholly-owned subsidiary of Evotec AG), Two Corporate Drive, South San Francisco, United States
E-mail: mattduncton@yahoo.com
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Med. Chem. Commun., 2011,2, 1135-1161
DOI:
10.1039/C1MD00134E
Received
24 May 2011,
Accepted
03 Jul 2011
First published online
22 Aug 2011
The addition of a radical to a heteroaromatic base is commonly referred to as a Minsici reaction. Such reactions constitute a broad-set of selective CH-functionalization processes. This review describes some of the major applications of Minisci reactions and related processes to medicinal or biological chemistry, and highlights some potential developments within this area.
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