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Issue 12, 2011
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Minisci reactions: Versatile CH-functionalizations for medicinal chemists

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Abstract

The addition of a radical to a heteroaromatic base is commonly referred to as a Minsici reaction. Such reactions constitute a broad-set of selective CH-functionalization processes. This review describes some of the major applications of Minisci reactions and related processes to medicinal or biological chemistry, and highlights some potential developments within this area.

Graphical abstract: Minisci reactions: Versatile CH-functionalizations for medicinal chemists

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Publication details

The article was received on 24 May 2011, accepted on 03 Jul 2011 and first published on 22 Aug 2011


Article type: Review Article
DOI: 10.1039/C1MD00134E
Citation: Med. Chem. Commun., 2011,2, 1135-1161
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    Minisci reactions: Versatile CH-functionalizations for medicinal chemists

    M. A. J. Duncton, Med. Chem. Commun., 2011, 2, 1135
    DOI: 10.1039/C1MD00134E

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