Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome†
Abstract
Identification of the cellular target of small molecules is a major challenge to developing biological tools and
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* Corresponding authors
a Chemical Genetics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198, Japan
b Graduate School of Science and Engineering, Saitama University, Saitama, Saitama 338-8570, Japan
c
Chemical Genomics Research Group, RIKEN Advanced Science Institute, Wako, Saitama 351-0198, Japan
E-mail:
yoshidam@riken.jp
Tel: +81 48-467-9516
d Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8572, Japan
e
Banting and Best Department of Medical Research, and Department of Molecular Genetics, Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 1A7, Canada
E-mail:
charlie.boone@utoronto.ca
Tel: +1 416-946-7260
Identification of the cellular target of small molecules is a major challenge to developing biological tools and
Y. Arita, S. Nishimura, A. Matsuyama, Y. Yashiroda, T. Usui, C. Boone and M. Yoshida, Mol. BioSyst., 2011, 7, 1463 DOI: 10.1039/C0MB00326C
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