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Issue 16, 2011
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Disposable microfluidic substrates: Transitioning from the research laboratory into the clinic

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Abstract

As more microfluidic applications emerge for clinical diagnostics, the choice of substrate and production method must be considered for eventual regulatory approval. In this review, we survey recent developments in disposable microfluidic substrates and their fabrication methods. We note regulatory approval for disposable microfluidic substrates will be more forthcoming if the substrates are developed with the United States Pharmacopeia's biocompatibility compliance guidelines in mind. We also review the recent trend in microfluidic devices constructed from a hybrid of substrates that takes advantage of each material's attributes.

Graphical abstract: Disposable microfluidic substrates: Transitioning from the research laboratory into the clinic

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Publication details

The article was received on 13 Feb 2011, accepted on 08 Jun 2011 and first published on 05 Jul 2011


Article type: Critical Review
DOI: 10.1039/C1LC20125E
Citation: Lab Chip, 2011,11, 2656-2665
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    Disposable microfluidic substrates: Transitioning from the research laboratory into the clinic

    J. S. Kuo and D. T. Chiu, Lab Chip, 2011, 11, 2656
    DOI: 10.1039/C1LC20125E

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