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Issue 17, 2011
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A microchip-based model wound with multiple types of cells

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Abstract

Collective migration is critical to many physiological processes, but few methods allow for studying this behavior with precisely controlled cell–cell interaction. Here we report the development of a microchip based on co-culture of different types of cells and selective injury, and explore the dynamics of epithelial collective migration triggered by a real cell group.

Graphical abstract: A microchip-based model wound with multiple types of cells

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Publication details

The article was received on 04 Nov 2010, accepted on 22 Jun 2011 and first published on 21 Jul 2011


Article type: Communication
DOI: 10.1039/C0LC00562B
Citation: Lab Chip, 2011,11, 2819-2822
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    A microchip-based model wound with multiple types of cells

    Y. Xie, W. Zhang, L. Wang, K. Sun, Y. Sun and X. Jiang, Lab Chip, 2011, 11, 2819
    DOI: 10.1039/C0LC00562B

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