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Issue 4, 2011
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Dielectrophoresis of Caenorhabditis elegans

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Abstract

We demonstrate for the first time the dielectrophoretic trapping and manipulation of a whole animal, the nematode Caenorhabditis elegans. We studied the effect of the electric field on the nematode as a function of field intensity and frequency. We identified a range of electric field intensities and frequencies that trap worms without apparent adverse effect on their viability. Worms tethered by dielectrophoresis (DEP) exhibit behavioral responses to blue light, indicating that at least some of the nervous system functions are unimpaired by the electrical field. DEP is useful to dynamically tether nematodes, sort nematodes according to size, and separate dead worms from live ones.

Graphical abstract: Dielectrophoresis of Caenorhabditis elegans

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Publication details

The article was received on 25 Oct 2010, accepted on 10 Dec 2010 and first published on 11 Jan 2011


Article type: Communication
DOI: 10.1039/C0LC00532K
Citation: Lab Chip, 2011,11, 599-604
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    Dielectrophoresis of Caenorhabditis elegans

    H. Chuang, D. M. Raizen, A. Lamb, N. Dabbish and H. H. Bau, Lab Chip, 2011, 11, 599
    DOI: 10.1039/C0LC00532K

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