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Issue 6, 2011
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A polyethylene oxide-functionalized self-organized alumina nanochannel array for an immunoprotection biofilter

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Abstract

Nanochannel membranes have been fabricated for many biological and engineering applications. However, due to low-throughput process, high cost, unsuitable pore geometries, and low chemical/mechanical stability, we could not have obtained optimized nanochannel membranes for biomedical treatments as well as a novel building block for artificial cell membranes. Here, we report a PEO-functionalized straight nanochannel array based on a self-organized porous alumina for a novel biofilter with antifouling, superior immunoprotection and high permeability of nutrients, which have excellent in vivo mechanical stability. Thus, our strategy may provide great advantages in novel membrane biotechnologies such as biofiltration, artificial cells, and drug delivery.

Graphical abstract: A polyethylene oxide-functionalized self-organized alumina nanochannel array for an immunoprotection biofilter

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Publication details

The article was received on 13 Oct 2010, accepted on 07 Jan 2011 and first published on 01 Feb 2011


Article type: Paper
DOI: 10.1039/C0LC00499E
Citation: Lab Chip, 2011,11, 1049-1053
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    A polyethylene oxide-functionalized self-organized alumina nanochannel array for an immunoprotection biofilter

    S. Lee, M. Park, H. Park, Y. Kim, S. Cho, J. H. Cho, J. Park and W. Hwang, Lab Chip, 2011, 11, 1049
    DOI: 10.1039/C0LC00499E

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