Jump to main content
Jump to site search

Issue 5, 2011
Previous Article Next Article

Sequencing transcriptomes in toto

Author affiliations

Abstract

The development of next-generation sequencing technologies has enabled the transcriptome to be measured and characterized at a level which was previously unattainable. Shot gun sequencing of RNAs, or RNA-Seq as it is known, is providing the means to simultaneously survey locus activity, transcript-specific expression, sequence content of transcripts and transcriptome discovery. This article discusses the current state of RNA-Seq, its potential for redefining transcriptomics and some of the challenges associated with this revolutionary technology.

Graphical abstract: Sequencing transcriptomes in toto

Back to tab navigation

Publication details

The article was received on 01 Jul 2010, accepted on 27 Dec 2010 and first published on 04 Feb 2011


Article type: Review Article
DOI: 10.1039/C0IB00062K
Citation: Integr. Biol., 2011,3, 522-528
  •   Request permissions

    Sequencing transcriptomes in toto

    K. S. Kassahn, N. Waddell and S. M. Grimmond, Integr. Biol., 2011, 3, 522
    DOI: 10.1039/C0IB00062K

Search articles by author

Spotlight

Advertisements