Jump to main content
Jump to site search

Issue 8, 2011
Previous Article Next Article

Epoxidation and Baeyer–Villiger oxidation using hydrogen peroxide and a lipase dissolved in ionic liquids

Author affiliations

Abstract

Epoxidation and Baeyer–Villiger oxidation of olefins and (cyclic) ketones were successfully carried out in hydrogen-bond-donating (HBD) ionic liquids, using a lipase-catalysed cascade and hydrogen peroxide as the terminal oxidant. The effect of the ionic liquids turned out to be twofold. The HBD ionic liquids exhibited a substantial positive solvent effect on the second step of the cascade, namely the oxygen transfer by peracid. In addition, we found that the Candida antarctica B lipase (CaLB) dissolved in 1-(3-hydroxypropyl)-3-methyl imidazolium nitrate 1a and 1-butyl-3-methylimidazolium nitrate 2a. This stable enzyme-ionic liquid solution opens the possibility for continuous chemical processing.

Graphical abstract: Epoxidation and Baeyer–Villiger oxidation using hydrogen peroxide and a lipase dissolved in ionic liquids

Back to tab navigation

Supplementary files

Publication details

The article was received on 08 Mar 2011, accepted on 12 May 2011 and first published on 29 Jun 2011


Article type: Paper
DOI: 10.1039/C1GC15255F
Citation: Green Chem., 2011,13, 2154-2160
  •   Request permissions

    Epoxidation and Baeyer–Villiger oxidation using hydrogen peroxide and a lipase dissolved in ionic liquids

    A. J. Kotlewska, F. van Rantwijk, R. A. Sheldon and I. W. C. E. Arends, Green Chem., 2011, 13, 2154
    DOI: 10.1039/C1GC15255F

Search articles by author

Spotlight

Advertisements