Issue 3, 2011
From the journal:

Green Chemistry

A metal-free decarboxylative cyclization from natural α-amino acids to constructpyridine derivatives†

Qiang Wang,a   Changfeng Wan,a   Yang Gu,a   Jintang Zhang,a   Lingfeng Gaoa  and  Zhiyong Wang*a  

* Corresponding authors

a Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry, Joint Laboratory of Green Synthetic Chemistry and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui, P. R. China
E-mail: zwang3@ustc.edu.cn
Fax: +86 551-360-3185
Tel: +86 551-360-3185

Abstract

A metal-free decarboxylative cyclization from natural α-amino acids was developed and applied in the preparation of pyridine derivatives. By virtue of this method, a series of pyridines containing the moiety of natural α-amino acids can be synthesized efficiently from the corresponding natural α-amino acids.

Graphical abstract: A metal-free decarboxylative cyclization from natural α-amino acids to construct pyridine derivatives

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Article information

DOI
https://doi.org/10.1039/C0GC00753F
Article type
Communication
Submitted
31 Oct 2010
Accepted
11 Jan 2011
First published
03 Feb 2011

Green Chem., 2011,13, 578-581

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A metal-free decarboxylative cyclization from natural α-amino acids to construct pyridine derivatives

Q. Wang, C. Wan, Y. Gu, J. Zhang, L. Gao and Z. Wang, Green Chem., 2011, 13, 578 DOI: 10.1039/C0GC00753F

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