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Issue 10, 2011
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Dietary chromones as antioxidant agents—the structural variable

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Abstract

This study reports an evaluation of the free radical scavenging ability of a series of chromone derivatives, in the light of their structural features and conformational behaviour. The 2,2-diphenyl-1-picrylhydrazyl radical (DPPH˙) test for the assessment of radical scavenging properties was applied, and the interpretation of the experimental results was assisted by ab initio theoretical approaches that allowed relevant parameters, such as the enthalpy of formation of the radical species, to be predicted. From the eighteen tested compounds, three—fisetin, luteolin and quercetin—are shown to act as effective antiradicals. Consistent structure–activity relationships (SARs) were established regarding the antioxidant role of this type of chromone-based system.

Graphical abstract: Dietary chromones as antioxidant agents—the structural variable

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Publication details

The article was received on 03 Jun 2011, accepted on 23 Jul 2011 and first published on 07 Sep 2011


Article type: Paper
DOI: 10.1039/C1FO10098J
Citation: Food Funct., 2011,2, 595-602
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    Dietary chromones as antioxidant agents—the structural variable

    M. M. Dias, N. F. L. Machado and M. P. M. Marques, Food Funct., 2011, 2, 595
    DOI: 10.1039/C1FO10098J

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