Jump to main content
Jump to site search

Issue 2, 2011
Previous Article Next Article

Well-defined copper(I) complexes for Click azide–alkyne cycloaddition reactions: one Click beyond

Author affiliations

Abstract

The discovery of copper(I) species as excellent catalysts for the regioselective cycloaddition reactions of azides and alkynes served as proof-of-concept of the importance of Click chemistry and opened a broad field of research that has found numerous ramifications in biochemistry, materials and medicinal science, for instance. The use of ligands in this context not only serves to stabilize the oxidation state of copper, but has also been shown to increase and modulate its reactivity. Still, efforts focused on developing more efficient catalytic systems for this transformation remain limited. Herein, the catalytic activities of ligated copper systems are reviewed in a way intended inspirational for further developments.

Graphical abstract: Well-defined copper(i) complexes for Click azide–alkyne cycloaddition reactions: one Click beyond

Back to tab navigation

Publication details

The article was received on 25 Nov 2010, accepted on 19 Dec 2010 and first published on 10 Feb 2011


Article type: Perspective
DOI: 10.1039/C0CY00064G
Citation: Catal. Sci. Technol., 2011,1, 166-178
  •   Request permissions

    Well-defined copper(I) complexes for Click azide–alkyne cycloaddition reactions: one Click beyond

    S. Díez-González, Catal. Sci. Technol., 2011, 1, 166
    DOI: 10.1039/C0CY00064G

Search articles by author

Spotlight

Advertisements