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Issue 12, 2011
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Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

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Abstract

This review provides an overview of a relatively new class of bio-conjugates, DNA amphiphiles, which consist of oligonucleotides covalently bonded to synthetic hydrophobic units. The reader will find the basic principles for the structural design and preparation methods of the materials. Moreover, the self-assembly into superstructures of higher order will be highlighted. Finally, some potential applications will be described.

Graphical abstract: Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

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Publication details

The article was received on 24 May 2011 and first published on 22 Aug 2011


Article type: Tutorial Review
DOI: 10.1039/C1CS15138J
Citation: Chem. Soc. Rev., 2011,40, 5745-5755
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    Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

    M. Kwak and A. Herrmann, Chem. Soc. Rev., 2011, 40, 5745
    DOI: 10.1039/C1CS15138J

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