Nanoscale chemical imaging of segregated lipid domains using tip-enhanced Raman spectroscopy

Lothar Opilik; Thomas Bauer; Thomas Schmid; Johannes Stadler; Renato Zenobi

doi:10.1039/C0CP02832K

This website uses cookies to give you the best user experience. If you continue without changing your settings we'll assume you are happy to receive all RSC cookies. You can change your cookie settings by navigating to our Privacy and Cookies page and following the instructions. These instructions are also obtainable from the privacy link at the bottom of any RSC page.

skip RSC | ChemSpider | Feedback

Home > Journals > Physical Chemistry Chem... > Nanoscale chemical imag...

For Authors & Referees | For Librarians | For Members

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Physical Chemistry Chemical Physics

Issue 21, 2011

High quality research in physical chemistry, chemical physics and biophysical chemistry.

Impact Factor 3.573 48 Issues per Year Indexed in MEDLINE

Journal Home

Previous Article | Next Article

Communication

Nanoscale chemical imaging of segregated lipid domains using tip-enhanced Raman spectroscopy

Lothar Opilik,^a Thomas Bauer,^b Thomas Schmid,^a Johannes Stadler^a and Renato Zenobi*^a

Show Affiliations

Hide Affiliations

Corresponding authors

Department of Chemistry and Applied Biosciences, ETH Zurich, CH-8093 Zurich, Switzerland
E-mail: zenobi@org.chem.ethz.ch ;
Fax: +41 44 6321292 ;
Tel: +41 44 6324377

Department of Materials, ETH Zurich, CH-8093 Zurich, Switzerland

Phys. Chem. Chem. Phys., 2011,13, 9978-9981

DOI: 10.1039/C0CP02832K
Received 09 Dec 2010, Accepted 09 Mar 2011
First published online 23 Mar 2011

This article is part of themed collection: Nano-bio: The interface between bio-systems and nano-devices and Biophysics and biophysical chemistry in PCCP

Please wait while Download options loads

Download Citation

Request Permissions

Abstract
Cited by
Compounds
Related Content

Lipid domains in supported lipid layers serve as a popular model to gain insight into the processes associated with the compartmentalization of biological membranes into so-called lipid rafts. In this paper, we present reproducible tip-enhanced Raman spectra originating from a very small number of molecules in a lipid monolayer on a gold surface, probed by the apex of a nanometer-sized silver tip. For the first time, we show large (128 × 128 pixels), high-resolution (< 50 nm) tip-enhanced Raman images of binary lipid mixtures with full spectral information at each pixel.

This may take some time to load.

Physical Chemistry Chemical Physics - Information Point

About this Journal

People and Contacts

Submit to this Journal

Editorial Board

Authors and Referees

Partner Societies

Subscription Information

Follow Journal | |

Supplementary Info

Experimental and data processing details, and additional figures
PDF (3575K)

Search Articles By

Lothar Opilik
Thomas Bauer
Thomas Schmid
Johannes Stadler
Renato Zenobi

Related Patents

View patents from SureChem

Terms & Conditions|Privacy and Cookies |Accessibility|ACAP Enabled

Physical Chemistry Chemical Physics

Nanoscale chemical imaging of segregated lipid domains using tip-enhanced Raman spectroscopy

Log in (Free Access)

Log in (Subscriber Access)

Supplementary Info

Search Articles By

Related Patents

Physical Chemistry Chemical Physics

Nanoscale chemical imaging of segregated lipid domains using tip-enhanced Raman spectroscopy

This text is added as a work around for heading error in Accessibility testing

Log in (Free Access)

Log in (Subscriber Access)

Supplementary Info

Search Articles By

Related Patents