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Issue 35, 2011
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High-throughput age synchronisation of Caenorhabditis elegans

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Abstract

We present a passive microfluidic strategy for sorting adult C. elegans nematodes on the basis of age and size. The separation mechanism takes advantage of phenotypic differences between ‘adult’ and ‘juvenile’ organisms and their behaviour in microfluidic architectures. In brief, the microfluidic device allows worms to sort themselves in a passive manner.

Graphical abstract: High-throughput age synchronisation of Caenorhabditis elegans

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Publication details

The article was received on 07 Jul 2011, accepted on 20 Jul 2011 and first published on 05 Aug 2011


Article type: Communication
DOI: 10.1039/C1CC14076K
Citation: Chem. Commun., 2011,47, 9801-9803
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    High-throughput age synchronisation of Caenorhabditis elegans

    X. C. I. Solvas, F. M. Geier, A. M. Leroi, J. G. Bundy, J. B. Edel and A. J. deMello, Chem. Commun., 2011, 47, 9801
    DOI: 10.1039/C1CC14076K

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