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Issue 37, 2011
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Separation of proteins using supramolecular gel electrophoresis

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Abstract

An amphiphilic low-molecular-weight hydrogelator 1 was synthesized. A tris-glycine-SDS solution gel of 1 was applied for electrophoresis to separate proteins. Centrifugation of a mixture of protein and a hydrogel of 1 enabled the recovery of protein. Various combinations of proteins were applied for supramolecular gel electrophoresis (SUGE), and remarkably poor mobility for small proteins (<45 kDa) was found.

Graphical abstract: Separation of proteins using supramolecular gel electrophoresis

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Publication details

The article was received on 27 Jun 2011, accepted on 08 Aug 2011 and first published on 19 Aug 2011


Article type: Communication
DOI: 10.1039/C1CC13826J
Citation: Chem. Commun., 2011,47, 10344-10346
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    Separation of proteins using supramolecular gel electrophoresis

    S. Yamamichi, Y. Jinno, N. Haraya, T. Oyoshi, H. Tomitori, K. Kashiwagi and M. Yamanaka, Chem. Commun., 2011, 47, 10344
    DOI: 10.1039/C1CC13826J

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