Highly efficient construction of spirocyclic chromanone –pyrrolidinesviaCu(I)/TF–BiphamPhos-catalyzed asymmetric 1,3-dipolar cycloaddition
Abstract
A facile synthesis of highly functional spiro-[4-chromanone-3,3′-pyrrolidine] bearing one unique spiro quarternary and three tertiary stereogenic centers is developed in excellent stereoselectivity for the first time.
Fetching data from CrossRef.