Issue 32, 2011
From the journal:

Chemical Communications

Hot-injection synthesis of iron/iron oxide core/shell nanoparticles for T2 contrast enhancement in magnetic resonance imaging†

David A. J. Herman,a   Peter Ferguson,b   Soshan Cheong,ac   Ian F. Hermans,b   Ben J. Ruck,a   Kathryn M. Allan,a   Sujay Prabakar,a   John L. Spencer,a   Conrad D. Lendrumc  and  Richard. D. Tilley*a  

* Corresponding authors

a School of Chemical and Physical Sciences and The MacDiarmid Institute of Advanced Materials and Nanotechnology, Victoria University of Wellington, P.O. Box 600, Wellington, New Zealand
E-mail: richard.tilley@vuw.ac.nz

b Malaghan Institute of Medical Research, P.O. Box 7060, Wellington, New Zealand

c Industrial Research Limited, P.O. Box 31-310, Lower Hutt, New Zealand

Abstract

Here we report a new, bench-top synthesis for iron/iron oxide core/shell nanoparticlesvia the thermal decomposition of Fe(η5-C6H3Me4)2. The iron/iron oxide core/shell nanoparticles are superparamagnetic at room temperature and show improved negative contrast in T2-weighted MR imaging compared to pure iron oxides nanoparticles, and have a transverse relaxivity (r2) of 332 mM−1 s−1.

Graphical abstract: Hot-injection synthesis of iron/iron oxide core/shell nanoparticles for T2 contrast enhancement in magnetic resonance imaging

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Article information

DOI
https://doi.org/10.1039/C1CC13416G
Article type
Communication
Submitted
09 Jun 2011
Accepted
29 Jun 2011
First published
15 Jul 2011

Chem. Commun., 2011,47, 9221-9223

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Hot-injection synthesis of iron/iron oxide core/shell nanoparticles for T2 contrast enhancement in magnetic resonance imaging

D. A. J. Herman, P. Ferguson, S. Cheong, I. F. Hermans, B. J. Ruck, K. M. Allan, S. Prabakar, J. L. Spencer, C. D. Lendrum and Richard. D. Tilley, Chem. Commun., 2011, 47, 9221 DOI: 10.1039/C1CC13416G

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