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Issue 32, 2011
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GeT peptides: a single-domain approach to gene delivery

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Abstract

A generic peptide sequence for gene delivery is described. The sequence penetrates eukaryotic cells and promotes active DNA transport into mammalian cells (EGFP positive) by undergoing differential membrane-induced folding, which renders it both endosomolytic and antibacterial.

Graphical abstract: GeT peptides: a single-domain approach to gene delivery

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Publication details

The article was received on 24 May 2011, accepted on 04 Jul 2011 and first published on 18 Jul 2011


Article type: Communication
DOI: 10.1039/C1CC13043A
Citation: Chem. Commun., 2011,47, 9045-9047
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    GeT peptides: a single-domain approach to gene delivery

    B. Lamarre, J. Ravi and M. G. Ryadnov, Chem. Commun., 2011, 47, 9045
    DOI: 10.1039/C1CC13043A

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