Jump to main content
Jump to site search

Issue 29, 2011
Previous Article Next Article

Direct substitution of the hydroxy group with highly functionalized nitrogen nucleophiles catalyzed by Au(III)

Author affiliations

Abstract

A direct catalytic substitution of various allylic and benzylic alcohols with synthetically useful, but acid-sensitive Boc, Bus, and Dios protected amine nucleophiles, which have not been well utilized for Lewis acid catalysis, with various functionalities (OTBS, OTHP, etc.) was efficiently catalyzed by 1 mol% of Au(III) under mild conditions.

Graphical abstract: Direct substitution of the hydroxy group with highly functionalized nitrogen nucleophiles catalyzed by Au(iii)

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 May 2011, accepted on 31 May 2011 and first published on 21 Jun 2011


Article type: Communication
DOI: 10.1039/C1CC12760H
Citation: Chem. Commun., 2011,47, 8322-8324
  •   Request permissions

    Direct substitution of the hydroxy group with highly functionalized nitrogen nucleophiles catalyzed by Au(III)

    T. Ohshima, Y. Nakahara, J. Ipposhi, Y. Miyamoto and K. Mashima, Chem. Commun., 2011, 47, 8322
    DOI: 10.1039/C1CC12760H

Search articles by author

Spotlight

Advertisements