Thiourea isosteres as anion receptors and transmembrane transporters

Marco Wenzel; Mark E. Light; Anthony P. Davis; Philip A. Gale

doi:10.1039/C1CC12439K

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Chemical Communications

Issue 27, 2011

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Thiourea isosteres as anion receptors and transmembrane transporters

Marco Wenzel , Mark E. Light , Anthony P. Davis and Philip A. Gale

Chem. Commun., 2011, 47, 7641-7643

DOI: 10.1039/C1CC12439K
Received 26 Apr 2011, Accepted 24 May 2011
First published on the web 09 Jun 2011

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Compounds containing cyanoguanidine and 3-amino-1,2,4-benzothiadiazine-1,1-dioxide have been studied as anion receptors and transporters. Significant affinity for oxo-anions was observed in organic solution and the receptors were found to function as transmembrane chloride/nitrate antiporters with transport rates enhanced in the presence of valinomycin–K⁺ complex.

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Chemical Communications

Thiourea isosteres as anion receptors and transmembrane transporters

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