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Issue 28, 2011
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Designing label-free DNA sequences to achieve controllable turn-off/on fluorescence response for Hg2+ detection

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Abstract

Controllable turn off/on fluorescent sensors for Hg2+ detection were developed by designing different label-free DNA sequences and using the minor groove dye of DAPI. These assays exhibit high sensitivity and selectivity, with the detection limits of 5 nM and 1.5 nM for turn off and turn on sensors, respectively.

Graphical abstract: Designing label-free DNA sequences to achieve controllable turn-off/on fluorescence response for Hg2+ detection

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Publication details

The article was received on 24 Apr 2011, accepted on 25 May 2011 and first published on 14 Jun 2011


Article type: Communication
DOI: 10.1039/C1CC12384J
Citation: Chem. Commun., 2011,47, 8010-8012
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    Designing label-free DNA sequences to achieve controllable turn-off/on fluorescence response for Hg2+ detection

    Z. Zhu, L. Xu, X. Zhou, J. Qin and C. Yang, Chem. Commun., 2011, 47, 8010
    DOI: 10.1039/C1CC12384J

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