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Issue 27, 2011
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Pd-mediated new synthesis of pyrroles: their evaluation as potential inhibitors of phosphodiesterase 4

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Abstract

A sequential Pd-mediated multi-component reaction followed by Suzuki or Heck or Sonogashira coupling in a single pot has been developed for the synthesis of functionalized pyrroles as potential inhibitors of PDE4.

Graphical abstract: Pd-mediated new synthesis of pyrroles: their evaluation as potential inhibitors of phosphodiesterase 4

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Publication details

The article was received on 21 Apr 2011, accepted on 17 May 2011 and first published on 03 Jun 2011


Article type: Communication
DOI: 10.1039/C1CC12321A
Citation: Chem. Commun., 2011,47, 7779-7781
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    Pd-mediated new synthesis of pyrroles: their evaluation as potential inhibitors of phosphodiesterase 4

    G. R. Reddy, T. R. Reddy, S. C. Joseph, K. S. Reddy, L. S. Reddy, P. M. Kumar, G. R. Krishna, C. M. Reddy, D. Rambabu, R. Kapavarapu, C. Lakshmi, T. Meda, K. K. Priya, K. V. L. Parsa and M. Pal, Chem. Commun., 2011, 47, 7779
    DOI: 10.1039/C1CC12321A

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