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Issue 28, 2011
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Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

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Abstract

A multimodal optical/paramagnetic nanoprobe, Den-Angio, was developed and demonstrated a capability to circumvent the blood brain barrier (BBB) and visualize brain tumors with high sensitivity in vivo. Den-Angio holds promise to pre-operatively localize brain tumors and make image-guided tumor resection possible during surgery.

Graphical abstract: Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

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Publication details

The article was received on 08 Apr 2011, accepted on 27 Apr 2011 and first published on 31 May 2011


Article type: Communication
DOI: 10.1039/C1CC12007G
Citation: Chem. Commun., 2011,47, 8130-8132
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    Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

    H. Yan, J. Wang, P. Yi, H. Lei, C. Zhan, C. Xie, L. Feng, J. Qian, J. Zhu, W. Lu and C. Li, Chem. Commun., 2011, 47, 8130
    DOI: 10.1039/C1CC12007G

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