Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 28, 2011
Previous Article Next Article

The effect of neat ionic liquid on the folding of short peptides

Author affiliations

Abstract

Using circular dichroism spectroscopy, we show evidence of unusual folding behaviour for several designed peptides in neat ionic liquid. Helical peptides, AKA2 and Trp-cage, exhibit heat-induced folding, with stable helical structure persisting to 96 °C, whereas the β-hairpin Trpzip4 is destabilized by the neat [C4mpy][Tf2N].

Graphical abstract: The effect of neat ionic liquid on the folding of short peptides

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 16 Mar 2011, accepted on 02 Jun 2011 and first published on 13 Jun 2011


Article type: Communication
DOI: 10.1039/C1CC11527H
Citation: Chem. Commun., 2011,47, 8007-8009
  •   Request permissions

    The effect of neat ionic liquid on the folding of short peptides

    J. Lin Huang, M. E. Noss, K. M. Schmidt, L. Murray and M. R. Bunagan, Chem. Commun., 2011, 47, 8007
    DOI: 10.1039/C1CC11527H

Search articles by author