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Issue 23, 2011
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Arginine conjugates of metallo-supramolecular cylinders prescribe helicity and enhance DNA junction binding and cellular activity

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Abstract

The conjugation of arginine residues at the ends of a metallo-supramolecular triple-helical cylinder enables absolute control over the helicity of the cylinder core, and boosts the DNA junction recognition by the complexes and their activity against a cancer cell line.

Graphical abstract: Arginine conjugates of metallo-supramolecular cylinders prescribe helicity and enhance DNA junction binding and cellular activity

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Publication details

The article was received on 08 Mar 2011, accepted on 20 Apr 2011 and first published on 09 May 2011


Article type: Communication
DOI: 10.1039/C1CC11356A
Citation: Chem. Commun., 2011,47, 6575-6577
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    Arginine conjugates of metallo-supramolecular cylinders prescribe helicity and enhance DNA junction binding and cellular activity

    L. Cardo, V. Sadovnikova, S. Phongtongpasuk, N. J. Hodges and M. J. Hannon, Chem. Commun., 2011, 47, 6575
    DOI: 10.1039/C1CC11356A

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